Welcome to HRTCafe.net, formerly DIYHRT.Cafe! We hope you enjoy your stay here. For mobile users, just tap the menu icon at the top left of the page to access links to specific medication pages. If you're on a laptop or desktop, you'll find the links in the top menu. Additionally, this page also features a comprehensive list of suppliers along with detailed information about each of them.

Where do I begin?

We are currently working on adding resources on where to begin when it comes to selecting what to start with, general information regarding being trans, and more things to consider when starting DIY. However, until then a greatly respected resource is DIYHRT Directory Wiki.


Medication / Sourcing Information Main Use Important Notes
Estradiol Injections Estrogen Cheapest way to start HRT with minimal to no side effects.
Estradiol Pills Estrogen The most common estrogen.
Estradiol Gel Estrogen The best alternative to injections or pills.
Estradiol Patches Estrogen Can have shortage problems.
Spironolactone Anti-Androgen The most common Anti-Androgen perscribed in north america, anecdotally hated.
Bicalutamide Anti-Androgen Has the least major side effects of the anti-androgens.
Cyproterone Acetate Anti-Androgen Will tank testosterone levels, with some safety information to keep in mind.
GnRH Agonists Anti-Androgen One of the best anti-androgens, however difficult to obtain and can be expensive. Can also be used as puberty blockers.
Progesterone Capsules Progesterone Easy to obtain however when taken orally (you can take them using... other methods) it can cause you to be sleepy.
Progesterone Gel Progesterone A lot harder to obtain than other methods but a good alternative to rectal or injections.
Progesterone Injections Progesterone Great way to get progesterone however it requires frequent injection (daily or every other day).
Finasteride Hair Loss Decreases DHT levels to prevent hair loss (NOT an anti-androgen) and is associated with mental health effects.
Dutasteride Hair Loss Decreases DHT levels to prevent hair loss (NOT an anti-androgen) and is associated with mental health effects.
Raloxifene SERM Complicated read info page before use.
Domperidone Dompamine Antagonist Do not use for breast growth, useful to induce lactation.

Homebrew Vendors

We recommend ordering from vendors which ship from the region you reside in. This will result in getting medication faster with essentially no risk of your package being seized.

The following homebrewers also ship worldwide:

Seller Info Ship-To From Payment
Felicitas Info EU Germany BTC, ETH, LTC, XMR
Girlpotion Info EU EU BTC, LTC, XMR
Silver Maple Labs
Voix Celeste
Otokonoko Pharmaceuticals Info Worldwide Brazil BCH, BTC, DOGE, ETH, LTC, USDC, XMR, XRP
TeaHRT TOR Info United States United States BCH, BTC, ETH, LTC, XMR
Vanna Pharma Info UK UK BCH, BNB, BTC, ETH, LTC, XMR, ZEC
Astrovials TOR Info Worldwide France BTC, ETH, LTC

Pharmaceutical Vendors

These vendors are unregulated Internet pharmacies. They obtain medications prepared by actual, regulated pharmaceutical manufacturers and resell them without a prescription.

Seller Info Ship-To From Payment
4NRX Phrmacy Info UK Hong Kong Credit Card
Aipctshop Info Worldwide India Credit Card, BTC, ETH, LTC, Bank
All Day Chemist Info Worldwide India BTC, ETH, Bank
Amazing4Health Info Worldwide Thailand Wise, Bank
Bulgarian Online Pharmacy Info Worldwide EU BTC, Bank
DashPCT Info Worldwide Multiple BCH, BTC, DOGE, ETH, LTC, SOL, XMR, Wise
Dragon Ordnance Info Worldwide Multiple BCH, BTC, DOGE, ETH, LTC, SOL, XMR, Wise
Favskinhouse Info Worldwide Thailand Bank
HealthyAreaStore Info Worldwide Thailand BTC, USDT
Inhouse Pharmacy Info Worldwide Vanuatu eCheck, AUD, EUR, GBP, USD
Japan Health Center (Bio-Japan) Info Worldwide Japan BTC, Bank
Medicina Mexico Info Worldwide Mexico AUD, MXN, USD, BCH, BTC, ETH, LTC
Pharmacy House Info Worldwide Russia Bank, BTC
Pilloid Info Worldwide Russia BTC
ReliableRx Pharmacy Info Worldwide India BTC, ETH, USD
RxAisle Info Worldwide Turkey Credit Card, BTC, Bank
ShapeShifter Info Worldwide EU BTC
Silhouette Beauty Info Worldwide Portugal BTC
United Pharmacies (NL) Info Netherlands Hong Kong BTC
United Pharmacies (UK) Info United Kingdom Hong Kong Bank, BTC
United Pharmacies (US) Info United States Hong Kong Bank, BTC
Web Order Pharmacy (UK) Info United Kingdom India BTC
Web Order Pharmacy (US) Info United States India BTC

Unverified Vendors

These vendors are not verified because they are newer.

Seller Info Reason
MyCare RX No third party testing.
Fiolelabs Lack of public reviews, all practices match verification.

These vendors are not verified and not recomended for various reasons. (Generally only vendors some might expect to be on the site are here).

Seller Info Reason
Lena Info Unsafe production process.
Serapharma Lack of information about vendor.
Purple Panda Currently under consideration.

DIY Homebrew

Homebrew can be useful to learn how things are compounded; the main page of our compounding section can be found here.

HRT Cafe Contributors

It is important to note major contributions people have helped to make the cafe what it is.

Username Contact Contribution
Admin [email protected] Daily maintainer since feb 2024.
GS Girl Redacted Helps with technical issues.
Redacted Redacted Helped majorly to make the new web scraper bot in 2/2024.
Redacted Redacted Rewrote and reformatted HRT homebrew guides made public in 3/2024, did most initial technical stuff for the new site in 2/2024 (also worked on scraper bot).